Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.89 |
| ▸ | GLA | P06280 | 1/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | POLB | P06746 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14420673 | 0.94 | SMN1; SMN2 (1.00) | SMN1; SMN2GLAALDH1A1POLBLMNA | |
| SCHEMBL3457699 | 0.94 | GLA (1.00) | SMN1; SMN2GLAALDH1A1POLBLMNA | |
| SCHEMBL26187344 | 0.81 | SMN1; SMN2 (0.60) | SMN1; SMN2GLAALDH1A1POLBLMNA | |
| SCHEMBL14095110 | 0.80 | SMN1; SMN2 (0.71) | SMN1; SMN2GLAALDH1A1POLBLMNA | |
| SCHEMBL7365835 | 0.79 | SMN1; SMN2 (0.58) | SMN1; SMN2GLAALDH1A1POLBLMNA | |
| SCHEMBL7899265 | 0.79 | SMN1; SMN2 (0.57) | SMN1; SMN2GLAALDH1A1POLBLMNA | |
| SCHEMBL7399374 | 0.77 | SMN1; SMN2 (0.56) | SMN1; SMN2GLAALDH1A1POLBLMNA | |
| SCHEMBL13826099 | 0.76 | GLA (0.68) | SMN1; SMN2GLAALDH1A1POLBLMNA | |
| SCHEMBL10720608 | 0.76 | TSHR (0.69) | SMN1; SMN2GLAALDH1A1POLBKMT2A | |
| SCHEMBL30441719 | 0.75 | SMN1; SMN2 (0.60) | SMN1; SMN2GLAALDH1A1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023199238-A1 | NOVEL COMPOUNDS TO TREAT CYTOKINE RELATED DISORDERS | ZYDUS LIFESCIENCES LIMITED (IN) | 2023-10-19 | — | — | WO | disclosed |