Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | RAF1 | P04049 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365835 | 0.99 | SMN1; SMN2 (0.58) | SMN1; SMN2GLAKMT2AATMALDH1A1 | |
| SCHEMBL7367675 | 0.88 | MAPT (0.51) | SMN1; SMN2GLAKMT2AATMALDH1A1 | |
| SCHEMBL30610018 | 0.77 | SMN1; SMN2 (0.89) | SMN1; SMN2GLAKMT2AATMALDH1A1 | |
| SCHEMBL21646124 | 0.74 | MAPT (0.56) | SMN1; SMN2KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL7367801 | 0.74 | ALDH1A1 (0.56) | SMN1; SMN2KMT2AATMALDH1A1L3MBTL1 | |
| SCHEMBL3457699 | 0.71 | GLA (1.00) | SMN1; SMN2GLAKMT2AATMALDH1A1 | |
| SCHEMBL14420673 | 0.71 | SMN1; SMN2 (1.00) | SMN1; SMN2GLAKMT2AATMALDH1A1 | |
| SCHEMBL7364179 | 0.70 | SMN1; SMN2 (0.49) | SMN1; SMN2GLAKMT2AATMALDH1A1 | |
| SCHEMBL7369067 | 0.69 | SMN1; SMN2 (0.51) | SMN1; SMN2GLAKMT2AATMALDH1A1 | |
| SCHEMBL7364181 | 0.68 | ALDH1A1 (0.48) | SMN1; SMN2ATMALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018764-A1 | DIHYDROBENZOANTHRACENONE, -PYRIMIDINONE OR DIHYDRONAPHTOQUINOLINONE | MERCK PATENT GMBH (DE) | 1998-05-07 | — | — | WO | disclosed |