Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.69 |
| ▸ | FLT1 | P17948 | 2/20 | 0.69 |
| ▸ | MKNK1 | Q9BUB5 | 8/20 | 0.62 |
| ▸ | RET | P07949 | 1/20 | 0.57 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.56 |
| ▸ | FADS1 | O60427 | 1/20 | 0.54 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.50 |
| ▸ | CDC7 | O00311 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13434860 | 1.00 | EGFR (0.69) | EGFRFLT1MKNK1RETROCK2 | |
| SCHEMBL22946710 | 0.90 | EGFR (0.62) | EGFRFLT1MKNK1RETROCK2 | |
| SCHEMBL3035598 | 0.82 | ROCK2 (0.60) | EGFRFLT1MKNK1RETROCK2 | |
| SCHEMBL5461595 | 0.81 | EGFR (1.00) | EGFRFLT1FADS1PIP4K2C | |
| SCHEMBL30611453 | 0.81 | MKNK1 (0.69) | EGFRFLT1MKNK1RETROCK2 | |
| SCHEMBL4035154 | 0.79 | MKNK1 (0.55) | EGFRFLT1MKNK1RETROCK2 | |
| SCHEMBL13220437 | 0.78 | ROCK2 (0.54) | EGFRFLT1MKNK1ROCK2ROCK1 | |
| SCHEMBL13434870 | 0.78 | MKNK1 (0.60) | EGFRFLT1MKNK1RETCDC7 | |
| SCHEMBL2835747 | 0.78 | EGFR (0.74) | EGFRFLT1MKNK1RETROCK2 | |
| SCHEMBL29516907 | 0.78 | EGFR (0.74) | EGFRFLT1MKNK1RETROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111587112-B | Rho-related inhibitors of coiled-coil-containing protein kinases | 卡德门企业有限公司 | 2023-10-10 | — | — | CN | disclosed |