Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 18/20 | 0.77 |
| ▸ | ROCK1 | Q13464 | 10/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20784054 | 1.00 | ROCK2 (0.77) | ROCK2ROCK1 | |
| SCHEMBL30611506 | 0.94 | ROCK2 (0.76) | ROCK2ROCK1 | |
| SCHEMBL20774718 | 0.94 | ROCK2 (0.76) | ROCK2ROCK1 | |
| SCHEMBL20784023 | 0.89 | ROCK2 (0.69) | ROCK2ROCK1 | |
| SCHEMBL30611472 | 0.89 | ROCK2 (0.69) | ROCK2ROCK1 | |
| SCHEMBL20774611 | 0.89 | ROCK2 (0.69) | ROCK2ROCK1 | |
| SCHEMBL30611482 | 0.88 | ROCK2 (0.68) | ROCK2ROCK1 | |
| SCHEMBL20774716 | 0.88 | ROCK2 (0.68) | ROCK2ROCK1 | |
| SCHEMBL20774724 | 0.87 | ROCK2 (0.71) | ROCK2ROCK1 | |
| SCHEMBL20774602 | 0.87 | ROCK2 (1.00) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111587112-B | Rho-related inhibitors of coiled-coil-containing protein kinases | 卡德门企业有限公司 | 2023-10-10 | — | — | CN | disclosed |