Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CD38 | P28907 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26107710 | 1.00 | KDM4E (0.52) | KDM4ENR4A2BRD4ALDH1A1SMN1; SMN2 | |
| SCHEMBL31347186 | 0.86 | KDM4E (0.49) | KDM4EALDH1A1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL26105230 | 0.86 | KDM4E (0.49) | KDM4EALDH1A1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL31347137 | 0.85 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL30612114 | 0.85 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL30611844 | 0.85 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2HPGDTSHR | |
| SCHEMBL26107749 | 0.85 | KDM4E (0.57) | KDM4EALDH1A1NPC1GAAMAPT | |
| SCHEMBL31347211 | 0.85 | KDM4E (0.57) | KDM4EALDH1A1NPC1GAAMAPT | |
| SCHEMBL26105877 | 0.85 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2HPGDTSHR | |
| SCHEMBL26107397 | 0.85 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585252-A | Bicyclic heteroaryl containing compounds as IKZF2 degrading agents | 翁科皮亚治疗公司和SK生命科学实验室 | 2025-03-07 | — | — | CN | disclosed |
| EP-4499629-A1 | BICYCLIC HETEROARYL-CONTAINING COMPOUNDS AS IKZF2 DEGRADERS | Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) | 2025-02-05 | — | — | EP | disclosed |
| WO-2023183919-A1 | BICYCLIC HETEROARYL-CONTAINING COMPOUNDS AS IKZF2 DEGRADERS | ONCOPIA THERAPEUTICS, INC. D/B/A PROTEOVANT THERAPEUTICS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |