Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26107749 | 1.00 | KDM4E (0.57) | KDM4EPLA2G2AMAPTPOLBP2RX7 | |
| SCHEMBL31347138 | 0.86 | KDM4E (0.50) | KDM4EPLA2G2AMAPTPOLBALDH1A1 | |
| SCHEMBL26108698 | 0.86 | KDM4E (0.50) | KDM4EPLA2G2AMAPTPOLBALDH1A1 | |
| SCHEMBL30611894 | 0.85 | KDM4E (0.52) | KDM4EPLA2G2AMAPTPOLBALDH1A1 | |
| SCHEMBL26107710 | 0.85 | KDM4E (0.52) | KDM4EPLA2G2AMAPTPOLBALDH1A1 | |
| SCHEMBL31347186 | 0.82 | KDM4E (0.49) | KDM4EPLA2G2AMAPTPOLBALDH1A1 | |
| SCHEMBL26105230 | 0.82 | KDM4E (0.49) | KDM4EPLA2G2AMAPTPOLBALDH1A1 | |
| SCHEMBL30612114 | 0.81 | KDM4E (0.48) | KDM4EPLA2G2AMAPTPOLBALDH1A1 | |
| SCHEMBL31347137 | 0.81 | KDM4E (0.48) | KDM4EPLA2G2AMAPTPOLBALDH1A1 | |
| SCHEMBL30611844 | 0.81 | KDM4E (0.48) | KDM4EPLA2G2AMAPTPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585252-A | Bicyclic heteroaryl containing compounds as IKZF2 degrading agents | 翁科皮亚治疗公司和SK生命科学实验室 | 2025-03-07 | — | — | CN | disclosed |