Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MPI | P34949 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26106823 | 1.00 | ALDH1A1 (0.34) | ALDH1A1CYP3A4CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL26106885 | 0.80 | ALDH1A1 (0.36) | ALDH1A1CYP3A4CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL30612231 | 0.80 | ALDH1A1 (0.36) | ALDH1A1CYP3A4CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL30612212 | 0.77 | ALDH1A1 (0.32) | ALDH1A1KDM4ESMN1; SMN2MEN1MAPT | |
| SCHEMBL26108115 | 0.77 | ALDH1A1 (0.32) | ALDH1A1KDM4ESMN1; SMN2MEN1MAPT | |
| SCHEMBL31347032 | 0.77 | CYP3A4 (0.35) | ALDH1A1CYP3A4CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL26106959 | 0.77 | CYP3A4 (0.35) | ALDH1A1CYP3A4CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL30611873 | 0.73 | KDM4E (0.32) | ALDH1A1KDM4E | |
| SCHEMBL26103813 | 0.73 | KDM4E (0.32) | ALDH1A1KDM4E | |
| SCHEMBL30612123 | 0.72 | ALDH1A1 (0.36) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585252-A | Bicyclic heteroaryl containing compounds as IKZF2 degrading agents | 翁科皮亚治疗公司和SK生命科学实验室 | 2025-03-07 | — | — | CN | disclosed |
| EP-4499629-A1 | BICYCLIC HETEROARYL-CONTAINING COMPOUNDS AS IKZF2 DEGRADERS | Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) | 2025-02-05 | — | — | EP | disclosed |
| WO-2023183919-A1 | BICYCLIC HETEROARYL-CONTAINING COMPOUNDS AS IKZF2 DEGRADERS | ONCOPIA THERAPEUTICS, INC. D/B/A PROTEOVANT THERAPEUTICS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |