Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 18/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | TTK | P33981 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31218678 | 0.83 | TYK2 (0.43) | TYK2PDE4DTTKHSD11B1 | |
| SCHEMBL31218783 | 0.82 | TYK2 (0.53) | TYK2PDE4D | |
| SCHEMBL31218847 | 0.80 | TYK2 (0.42) | TYK2PDE4D | |
| SCHEMBL31218735 | 0.77 | TYK2 (0.48) | TYK2PDE4DTTK | |
| SCHEMBL29754344 | 0.75 | TYK2 (0.77) | TYK2 | |
| SCHEMBL29754325 | 0.73 | TYK2 (0.62) | TYK2 | |
| SCHEMBL29754457 | 0.73 | TYK2 (0.64) | TYK2PDE4D | |
| SCHEMBL29754422 | 0.73 | TYK2 (0.62) | TYK2 | |
| SCHEMBL29754370 | 0.73 | TYK2 (0.62) | TYK2 | |
| SCHEMBL30612375 | 0.71 | KDM4C (0.41) | TYK2PDE4DTTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043164-A | Imidazopyridazine or pyrazolopyrimidine compounds and compositions | 安锐生物医药科技(广州)有限公司 | 2023-11-10 | — | — | CN | disclosed |