Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 17/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | TTK | P33981 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31218783 | 0.89 | TYK2 (0.53) | TYK2PDE4D | |
| SCHEMBL31218847 | 0.87 | TYK2 (0.42) | TYK2PDE4D | |
| SCHEMBL30612388 | 0.83 | TYK2 (0.41) | TYK2PDE4DTTKHSD11B1 | |
| SCHEMBL31218735 | 0.80 | TYK2 (0.48) | TYK2PDE4DTTK | |
| SCHEMBL30612375 | 0.78 | KDM4C (0.41) | TYK2PDE4DTTK | |
| SCHEMBL31218834 | 0.78 | TYK2 (0.49) | TYK2PDE4DTTK | |
| SCHEMBL29435834 | 0.77 | TYK2 (0.51) | TYK2PDE4DPDE4BTTK | |
| Hydrochloric Acid SCHEMBL30612394 | 0.76 | TYK2 (0.50) | TYK2PDE4DPDE4BTTK | |
| SCHEMBL27105633 | 0.70 | TYK2 (0.59) | TYK2PDE4D | |
| SCHEMBL26495339 | 0.70 | TYK2 (0.64) | TYK2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119013277-A | TYK2 degrading agent and application thereof | 凯麦拉医疗公司 | 2024-11-22 | — | — | CN | disclosed |