Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 3/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.39 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30983141 | 0.80 | TYK2 (0.47) | — | |
| SCHEMBL26098304 | 0.74 | PTPN1 (0.49) | KDM4EALDH1A1PTPN1HTTNPSR1 | |
| SCHEMBL30529592 | 0.72 | PTPN1 (0.41) | ALDH1A1PTPN1PARP1PIM1NTRK1 | |
| SCHEMBL11894259 | 0.70 | KDM4E (0.48) | KDM4EALDH1A1MAP2K1CLK4DYRK1B | |
| SCHEMBL23327537 | 0.70 | NR3C2 (0.38) | KDM4EALDH1A1PTPN1PARP1HTT | |
| SCHEMBL21811192 | 0.70 | KDM4E (0.44) | KDM4EALDH1A1PTPN1HTTNPSR1 | |
| SCHEMBL20689113 | 0.69 | TYK2 (0.44) | KDM4EALDH1A1MAP2K1CLK4DYRK1B | |
| SCHEMBL31245692 | 0.69 | POLB (0.39) | KDM4EALDH1A1NTRK1HTTNPSR1 | |
| SCHEMBL8335009 | 0.68 | TLR8 (0.73) | KDM4EALDH1A1MAP2K1CLK4DYRK1B | |
| SCHEMBL30184310 | 0.68 | MAPK13 (0.44) | KDM4EALDH1A1MAP2K1CLK4DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043164-A | Imidazopyridazine or pyrazolopyrimidine compounds and compositions | 安锐生物医药科技(广州)有限公司 | 2023-11-10 | — | — | CN | disclosed |