Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 19/20 | 0.47 |
| ▸ | JAK1 | P23458 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30983149 | 0.86 | TYK2 (0.45) | TYK2 | |
| SCHEMBL31572541 | 0.86 | TYK2 (0.45) | TYK2 | |
| SCHEMBL30612392 | 0.80 | KDM4E (0.49) | — | |
| SCHEMBL29990745 | 0.76 | TYK2 (0.64) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| SCHEMBL29990614 | 0.76 | TYK2 (0.64) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| SCHEMBL29990624 | 0.76 | TYK2 (0.64) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| SCHEMBL21960681 | 0.75 | TYK2 (0.62) | TYK2 | |
| SCHEMBL21947281 | 0.75 | TYK2 (0.62) | TYK2 | |
| SCHEMBL26099017 | 0.74 | TYK2 (0.46) | TYK2 | |
| SCHEMBL20689534 | 0.73 | TYK2 (0.66) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515674-A | Amide compound, preparation method thereof and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-08-20 | — | — | CN | disclosed |