Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SUCNR1 | Q9BXA5 | 8/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24302609 | 1.00 | MAPT (0.45) | MAPTSUCNR1ACACBACACATP53BP1 | |
| SCHEMBL24301589 | 1.00 | MAPT (0.45) | MAPTSUCNR1ACACBACACATP53BP1 | |
| SCHEMBL29025671 | 0.93 | MAPT (0.40) | MAPTSUCNR1TP53BP1HDAC1HDAC6 | |
| SCHEMBL30613466 | 0.93 | MAPT (0.40) | MAPTSUCNR1TP53BP1HDAC1HDAC6 | |
| SCHEMBL24301627 | 0.93 | MAPT (0.40) | MAPTSUCNR1TP53BP1HDAC1HDAC6 | |
| SCHEMBL24301576 | 0.89 | MAPT (0.46) | MAPTSUCNR1ACACBACACAHDAC1 | |
| SCHEMBL30613457 | 0.89 | MAPT (0.46) | MAPTSUCNR1ACACBACACAHDAC1 | |
| SCHEMBL30504329 | 0.89 | MAPT (0.46) | MAPTSUCNR1ACACBACACAHDAC1 | |
| SCHEMBL26667415 | 0.88 | HDAC1 (0.44) | MAPTTP53BP1CTSBCTSSCTSK | |
| SCHEMBL26667413 | 0.88 | HDAC1 (0.44) | MAPTTP53BP1CTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381146-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND USE THEREOF | HELIOS HUAMING BIOPHARMA CO., LTD. (CN) | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230381146-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND USE THEREOF | SSB, BTK, PADI6 | MAPT 790/4885SUCNR1 1963/4885ACACB 780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.