Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.33 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.30 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CHUK | O15111 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29091629 | 1.00 | TPMT (0.33) | TPMTMEP1BHSD17B1HSD17B2MEN1 | |
| SCHEMBL30615094 | 0.88 | RET (0.33) | TPMT | |
| SCHEMBL29091683 | 0.88 | RET (0.33) | TPMT | |
| SCHEMBL29091667 | 0.84 | CYP19A1 (0.32) | — | |
| SCHEMBL30615218 | 0.84 | CYP19A1 (0.32) | — | |
| SCHEMBL19115272 | 0.76 | — | — | |
| SCHEMBL22029169 | 0.76 | — | — | |
| SCHEMBL30101999 | 0.76 | — | — | |
| SCHEMBL29091591 | 0.75 | YTHDC1 (0.32) | CHUK | |
| SCHEMBL11213463 | 0.74 | PDE5A (0.49) | KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116925100-A | Substituted thiophenoquinolinone compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-10-24 | — | — | CN | disclosed |