Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.52 |
| ▸ | CNR1 | P21554 | 5/20 | 0.52 |
| ▸ | ACHE | P22303 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28496722 | 1.00 | CNR2 (0.52) | CNR2CNR1ACHEMAPTF2RL3 | |
| SCHEMBL14923635 | 0.91 | CNR2 (0.55) | CNR2CNR1ACHEMAPTF2RL3 | |
| SCHEMBL14923447 | 0.82 | CNR2 (0.52) | CNR2CNR1ACHEMAPTL3MBTL1 | |
| SCHEMBL30860213 | 0.81 | CNR2 (0.46) | CNR2CNR1ACHEMAPTF2RL3 | |
| SCHEMBL14908867 | 0.81 | CNR2 (0.46) | CNR2CNR1ACHEMAPTF2RL3 | |
| SCHEMBL30615548 | 0.81 | MAPT (0.53) | CNR2CNR1ACHEMAPTF2RL3 | |
| SCHEMBL28495928 | 0.81 | MAPT (0.53) | CNR2CNR1ACHEMAPTF2RL3 | |
| SCHEMBL264907 | 0.79 | ADORA2A (0.54) | CNR2CNR1ACHEMAPTL3MBTL1 | |
| SCHEMBL30615450 | 0.79 | ADORA2A (0.41) | CNR2CNR1ACHEMAPTELANE | |
| SCHEMBL28495400 | 0.79 | ADORA2A (0.41) | CNR2CNR1ACHEMAPTELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111868037-B | Fused cyclic urea derivatives as CRHR2 antagonists | 拉夸里亚创药株式会社 | 2023-10-13 | — | — | CN | disclosed |