Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 8/20 | 0.48 |
| ▸ | GABRD | O14764 | 8/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 8/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 8/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 8/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 8/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 8/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 8/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 8/20 | 0.48 |
| ▸ | GABRE | P78334 | 8/20 | 0.48 |
| ▸ | GABRA6 | Q16445 | 8/20 | 0.48 |
| ▸ | GABRG1 | Q8N1C3 | 8/20 | 0.48 |
| ▸ | GABRG3 | Q99928 | 8/20 | 0.48 |
| ▸ | GABRQ | Q9UN88 | 8/20 | 0.48 |
| ▸ | DAO | P14920 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16657379 | 0.82 | DAO (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL18386901 | 0.78 | GABRP (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL21464280 | 0.74 | HRH3 (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL16657378 | 0.72 | GABRP (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30615708 | 0.72 | HRH3 (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28488050 | 0.72 | HRH3 (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL21464136 | 0.70 | DAO (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11356818 | 0.69 | DAO (0.60) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30615654 | 0.69 | GABRP (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5433505 | 0.68 | HSP90AA1 (0.70) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111868037-B | Fused cyclic urea derivatives as CRHR2 antagonists | 拉夸里亚创药株式会社 | 2023-10-13 | — | — | CN | disclosed |