Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 16/20 | 0.62 |
| ▸ | ATF1 | P18846 | 14/20 | 0.62 |
| ▸ | JUN | P05412 | 3/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.54 |
| ▸ | RELA | Q04206 | 3/20 | 0.54 |
| ▸ | XPO1 | O14980 | 3/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1549128 | 1.00 | KDM4E (0.71) | KDM4ENFKB1ATF1JUNNFKB2 | |
| SCHEMBL26863419 | 0.90 | KDM4E (0.58) | KDM4ENFKB1ATF1JUNNFKB2 | |
| SCHEMBL8394437 | 0.89 | KDM4E (0.56) | KDM4ENFKB1ATF1JUNNFKB2 | |
| SCHEMBL4886213 | 0.87 | KDM4E (0.53) | KDM4ENFKB1ATF1JUNNFKB2 | |
| SCHEMBL2119119 | 0.85 | KDM4E (0.74) | KDM4ENFKB1ATF1JUNNFKB2 | |
| SCHEMBL8543216 | 0.84 | KDM4E (0.72) | KDM4ENFKB1ATF1JUNNFKB2 | |
| SCHEMBL4592592 | 0.84 | KDM4E (0.72) | KDM4ENFKB1ATF1JUNNFKB2 | |
| SCHEMBL473934 | 0.84 | ATF1 (0.62) | KDM4ENFKB1ATF1JUNNFKB2 | |
| SCHEMBL25415290 | 0.83 | KDM4E (0.71) | KDM4ENFKB1ATF1JUNNFKB2 | |
| Water SCHEMBL4592788 | 0.83 | KDM4E (0.71) | KDM4ENFKB1ATF1JUNNFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111278821-B | Spiro compounds as farnesol X receptor modulators | 百时美施贵宝公司 | 2023-10-03 | — | — | CN | disclosed |