Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 10/20 | 0.53 |
| ▸ | ATF1 | P18846 | 6/20 | 0.53 |
| ▸ | JUN | P05412 | 4/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.45 |
| ▸ | RELA | Q04206 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | FOS | P01100 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30617280 | 0.90 | KDM4E (0.71) | KDM4ENFKB1ATF1JUNNFKB2 | |
| SCHEMBL1549128 | 0.90 | KDM4E (0.71) | KDM4ENFKB1ATF1JUNNFKB2 | |
| SCHEMBL4886213 | 0.89 | KDM4E (0.53) | KDM4ENFKB1ATF1JUNNFKB2 | |
| SCHEMBL8394437 | 0.88 | KDM4E (0.56) | KDM4ENFKB1ATF1JUNNFKB2 | |
| SCHEMBL476310 | 0.79 | ALDH1A1 (0.59) | KDM4ENFKB1ATF1ALDH1A1MEN1 | |
| SCHEMBL29922173 | 0.79 | ALDH1A1 (0.59) | KDM4ENFKB1ATF1ALDH1A1MEN1 | |
| SCHEMBL3435395 | 0.79 | RAB9A (0.53) | KDM4ENFKB1JUNNFKB2RELA | |
| SCHEMBL31391972 | 0.79 | RAB9A (0.53) | KDM4ENFKB1JUNNFKB2RELA | |
| SCHEMBL762026 | 0.78 | ALDH1A1 (0.51) | KDM4ENFKB1ATF1ALDH1A1MEN1 | |
| SCHEMBL31379759 | 0.78 | ALDH1A1 (0.51) | KDM4ENFKB1ATF1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382893-A1 | AMIDE DERIVATIVE HAVING ANTIVIRAL ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2023-11-30 | — | — | US | disclosed |
| US-20230382893-A1 | AMIDE DERIVATIVE HAVING ANTIVIRAL ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382893-A1 | AMIDE DERIVATIVE HAVING ANTIVIRAL ACTIVITY | ZC3HAV1, ZC3HAV1L, IFNAR1 | KDM4E 618/4885NFKB1 2121/4885ATF1 3055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.