Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20540458 | 1.00 | PTGDR2 (0.44) | PTGDR2HPGDALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL30457873 | 0.83 | PTGDR2 (0.44) | PTGDR2HPGDALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL21639308 | 0.83 | PTGDR2 (0.44) | PTGDR2HPGDALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL2771758 | 0.80 | PTGDR2 (0.48) | PTGDR2HPGDALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL20335399 | 0.80 | PTGDR2 (0.50) | PTGDR2HPGDALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL4645847 | 0.79 | PTGDR2 (0.47) | PTGDR2HPGDALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL28931504 | 0.78 | PTGDR2 (0.49) | PTGDR2HPGDALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL3224950 | 0.78 | HPGD (0.55) | PTGDR2HPGDALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL28649792 | 0.78 | PTGDR2 (0.43) | PTGDR2HPGDALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL12953379 | 0.78 | PTGDR2 (0.46) | PTGDR2HPGDALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118878461-A | PD-1/PD-L1 inhibitors | 吉利德科学公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-112041311-B | PD-1/PD-L1 inhibitors | 吉利德科学公司 | 2023-10-03 | — | — | CN | disclosed |