Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 3/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15883782 | 1.00 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3EPHX1NPC1 | |
| SCHEMBL8995188 | 0.76 | AHR (0.46) | SLC6A2SLC6A4SLC6A3EPHX1NPC1 | |
| SCHEMBL4137088 | 0.75 | MAPT (0.46) | SLC6A2SLC6A4SLC6A3MAPTMAOA | |
| SCHEMBL30479180 | 0.75 | MAPT (0.46) | SLC6A2SLC6A4SLC6A3MAPTMAOA | |
| SCHEMBL3307955 | 0.74 | NPC1 (0.47) | SLC6A2SLC6A4SLC6A3EPHX1NPC1 | |
| SCHEMBL26745466 | 0.74 | DDB1 (0.41) | SLC6A2SLC6A4SLC6A3CYP2A6CHRM1 | |
| SCHEMBL4286233 | 0.74 | MAPT (0.44) | SLC6A2SLC6A4SLC6A3EPHX1MAPT | |
| SCHEMBL20863593 | 0.73 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3CHRM1DRD2 | |
| SCHEMBL18000304 | 0.72 | AHR (0.48) | SLC6A2SLC6A4SLC6A3EPHX1NPC1 | |
| SCHEMBL15883779 | 0.71 | CYP19A1 (0.52) | SLC6A2SLC6A4SLC6A3NPC1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111491930-B | Substituted Indole Compounds Useful as TLR Inhibitors | 百时美施贵宝公司 | 2023-09-26 | — | — | CN | disclosed |