Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 4/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8995188 | 0.98 | AHR (0.46) | NPC1EPHX1MAPTRAB9AHTR1D | |
| SCHEMBL18000304 | 0.91 | AHR (0.48) | NPC1EPHX1MAPTRAB9AAHR | |
| SCHEMBL22728599 | 0.84 | ESR2 (0.40) | NPC1EPHX1MAPTRAB9AHTR1D | |
| SCHEMBL3956097 | 0.84 | SLC6A2 (0.50) | AHRNR4A2CYP2A6F7LTA4H | |
| Hydrochloric Acid SCHEMBL28061431 | 0.83 | SLC6A2 (0.49) | AHRNR4A2CYP2A6F7LTA4H | |
| SCHEMBL4456373 | 0.83 | ESR2 (0.44) | NPC1MAPTRAB9AAHRNR4A2 | |
| SCHEMBL30461940 | 0.83 | SLC6A2 (0.46) | NPC1HTR1DAHRNR4A2CYP2A6 | |
| Ethoxycarbonyl Group SCHEMBL28291591 | 0.83 | EPHX1 (0.39) | NPC1EPHX1MAPTRAB9AHTR1D | |
| SCHEMBL12455980 | 0.81 | HTR3A (0.49) | AHRNR4A2CYP2A6F7LTA4H | |
| SCHEMBL14571687 | 0.80 | SLC6A4 (0.53) | HTR1DCHRM1DRD2KCNH2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025099444-A1 | N-Acetylserotonin (NAS) Analogues | Beckley Psytech Limited (GB) | 2025-05-15 | — | — | WO | disclosed |
| US-12150447-B2 | Plant growth regulator | UNIVERSITY OF WASHINGTON (US) | 2024-11-26 | — | — | US | disclosed |
| US-20210235697-A1 | PLANT GROWTH REGULATOR | UNIVERSITY OF WASHINGTON (US) | 2021-08-05 | — | — | US | disclosed |
| US-20210235697-A1 | PLANT GROWTH REGULATOR | UNIVERSITY OF WASHINGTON (US) | 2021-08-05 | — | — | US | disclosed |
| US-9029345-B2 | Selective inhibitors of translesion DNA replication | CASE WESTERN RESERVE UNIVERSITY (US) | 2015-05-12 | — | — | US | disclosed |
| US-20100111839-A1 | SELECTIVE INHIBITORS OF TRANSLESION DNA REPLICATION | BERDIS ANTHONY J | 2010-05-06 | — | — | US | disclosed |
| WO-2009145357-A1 | IN 1-POSITION DURCH EINEN RING SUBSTITUIERTE BENZO [1, 4] DIAZEPINE ZUR VERWENDUNGS ALS ANTIDEPRESSIVA | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2009-12-03 | — | — | WO | disclosed |
| WO-2008147454-A1 | SELECTIVE INHIBITORS OF TRANSLESION DNA REPLICATION | CASE WESTERN RESERVE UNIVERSITY (US) | 2008-12-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100111839-A1 | SELECTIVE INHIBITORS OF TRANSLESION DNA REPLICATION | RPA1, RPA3, PCNA | NPC1 1593/4885EPHX1 3319/4885MAPT 4299/4885 |
| US-20210235697-A1 | PLANT GROWTH REGULATOR | ING2, GHRHR, MYB | NPC1 4010/4885EPHX1 4250/4885MAPT 4124/4885 |
| US-12150447-B2 | Plant growth regulator | ING2, GHRHR, MYB | NPC1 4010/4885EPHX1 4250/4885MAPT 4124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.