Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 20/20 | 0.63 |
| ▸ | DDB1 | Q16531 | 19/20 | 0.63 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.63 |
| ▸ | TNF | P01375 | 1/20 | 0.63 |
| ▸ | IL1B | P01584 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30572353 | 0.88 | CRBN (0.67) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL26318074 | 0.87 | CRBN (0.66) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL2603174 | 0.86 | DDB1 (0.70) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL25344586 | 0.86 | CRBN (0.64) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL25345259 | 0.86 | CRBN (0.64) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL26317880 | 0.85 | DDB1 (0.69) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL25475645 | 0.85 | DDB1 (0.74) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL14218469 | 0.85 | DDB1 (0.74) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL21939264 | 0.84 | DDB1 (0.67) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL30572422 | 0.84 | CRBN (0.61) | CRBNDDB1IKZF3TNFIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116589445-A | Compound based on quinazoline substituted glutarimide skeleton and application thereof | 标新生物医药科技(上海)有限公司 | 2023-08-15 | — | — | CN | disclosed |