Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 13/20 | 0.51 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CKS1B | P61024 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30338582 | 0.77 | PTGS1 (0.46) | CTPS1MAP4K1PTGS1PTGS2CKS1B | |
| SCHEMBL30339084 | 0.77 | PTGS1 (0.46) | CTPS1MAP4K1PTGS1PTGS2CKS1B | |
| SCHEMBL21381576 | 0.73 | CTPS1 (0.43) | CTPS1MAP4K1PTGS1PTGS2SCN9A | |
| SCHEMBL30339221 | 0.69 | PTGS1 (0.44) | CTPS1MAP4K1PTGS1PTGS2SCN9A | |
| SCHEMBL31678766 | 0.69 | PTGS1 (0.44) | CTPS1MAP4K1PTGS1PTGS2SCN9A | |
| SCHEMBL30882868 | 0.68 | CTPS1 (1.00) | CTPS1 | |
| SCHEMBL21381439 | 0.68 | CTPS1 (1.00) | CTPS1 | |
| SCHEMBL20169526 | 0.68 | NPC1 (0.44) | KDM4EGLA | |
| SCHEMBL30882874 | 0.67 | CTPS1 (1.00) | CTPS1 | |
| SCHEMBL31678837 | 0.67 | PTGS1 (0.43) | CTPS1MAP4K1PTGS1PTGS2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116601131-A | CTPS1 inhibitor and application thereof | 林伯士克洛索有限公司 | 2023-08-15 | — | — | CN | disclosed |