Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 3/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | CTPS1 | P17812 | 7/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30339221 | 0.83 | PTGS1 (0.44) | PTGS1PTGS2CKS1BSKP2TDP1 | |
| SCHEMBL31678766 | 0.83 | PTGS1 (0.44) | PTGS1PTGS2CKS1BSKP2TDP1 | |
| SCHEMBL30339075 | 0.75 | TSHR (0.53) | PTGS1PTGS2CKS1BSKP2TDP1 | |
| SCHEMBL31678874 | 0.72 | PTGS1 (0.47) | PTGS1PTGS2CKS1BSKP2TDP1 | |
| SCHEMBL31678785 | 0.72 | PTGS1 (0.53) | PTGS1PTGS2CKS1BSKP2TDP1 | |
| SCHEMBL30338582 | 0.71 | PTGS1 (0.46) | PTGS1PTGS2CKS1BSKP2TDP1 | |
| SCHEMBL30339084 | 0.71 | PTGS1 (0.46) | PTGS1PTGS2CKS1BSKP2TDP1 | |
| SCHEMBL21381576 | 0.71 | CTPS1 (0.43) | PTGS1PTGS2CKS1BSKP2TDP1 | |
| SCHEMBL24369866 | 0.68 | TDP1 (0.48) | PTGS1PTGS2CKS1BSKP2TDP1 | |
| SCHEMBL25355967 | 0.67 | ABL1 (0.39) | PTGS1PTGS2CKS1BSKP2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250270200-A1 | CTPS1 INHIBITORS AND USES THEREOF | NIMBUS DISCOVERY, INC. | 2025-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250270200-A1 | CTPS1 INHIBITORS AND USES THEREOF | CTPS1, CTPS2, ECHS1 | PTGS1 1724/4885PTGS2 2086/4885CKS1B 149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.