Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 5/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CTPS1 | P17812 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | CTPS2 | Q9NRF8 | 1/20 | 0.42 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24088712 | 0.88 | CYP11B2 (0.49) | CYP11B2CYP11B1CTPS1CTPS2 | |
| SCHEMBL30455804 | 0.88 | CYP11B2 (0.49) | CYP11B2CYP11B1CTPS1CTPS2 | |
| SCHEMBL31676635 | 0.84 | CYP11B2 (0.48) | CYP11B2CYP11B1CTPS1CTPS2ALDH1A1 | |
| SCHEMBL24088755 | 0.84 | CYP11B2 (0.48) | CYP11B2CYP11B1CTPS1CTPS2ALDH1A1 | |
| SCHEMBL21044144 | 0.79 | CYP11B2 (0.50) | CYP11B2CYP11B1CTPS1CTPS2KDM4E | |
| SCHEMBL30416354 | 0.79 | CHEK1 (0.50) | MAPK1CTPS1 | |
| SCHEMBL32663050 | 0.79 | CYP11B2 (0.50) | CYP11B2CYP11B1CTPS1CTPS2KDM4E | |
| SCHEMBL24088666 | 0.76 | RXRB (0.53) | CYP11B2CYP11B1CTPS1KDM4E | |
| SCHEMBL30455283 | 0.76 | RXRB (0.53) | CYP11B2CYP11B1CTPS1KDM4E | |
| SCHEMBL22491812 | 0.76 | CTPS1 (0.54) | CYP11B2CYP11B1CTPS1CTPS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116601131-A | CTPS1 inhibitor and application thereof | 林伯士克洛索有限公司 | 2023-08-15 | — | — | CN | disclosed |