Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.60 |
| ▸ | CKS1B | P61024 | 2/20 | 0.52 |
| ▸ | SKP1 | P63208 | 2/20 | 0.52 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.52 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | RET | P07949 | 8/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16473496 | 0.86 | GPR119 (0.64) | GPR119CKS1BSKP1SKP2DDB1 | |
| SCHEMBL22581906 | 0.86 | GPR119 (0.60) | GPR119CKS1BSKP1SKP2DDB1 | |
| SCHEMBL1347359 | 0.83 | GPR119 (0.54) | GPR119CKS1BSKP1SKP2DDB1 | |
| SCHEMBL29376638 | 0.83 | GPR119 (0.54) | GPR119CKS1BSKP1SKP2DDB1 | |
| SCHEMBL30480343 | 0.83 | AKR1C3 (0.57) | GPR119CKS1BSKP1SKP2DDB1 | |
| SCHEMBL594352 | 0.83 | AKR1C3 (0.57) | GPR119CKS1BSKP1SKP2DDB1 | |
| SCHEMBL25188353 | 0.82 | RET (0.60) | GPR119CKS1BSKP1SKP2DDB1 | |
| SCHEMBL30930959 | 0.82 | GPR119 (0.50) | GPR119CKS1BSKP1SKP2MAP4K4 | |
| SCHEMBL31287119 | 0.82 | GPR119 (0.65) | GPR119CKS1BSKP1SKP2DDB1 | |
| SCHEMBL31185138 | 0.82 | RET (0.60) | GPR119CKS1BSKP1SKP2DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4434980-A1 | MULTIFUNCTIONAL COMPOUND CAPABLE OF DEGRADING BTK KINASE, AND COMPOSITION AND USE | Hangzhou HealZen Therapeutics Co., Ltd. (CN) | 2024-09-25 | — | — | EP | disclosed |
| WO-2024169871-A1 | BTK INHIBITOR AND USE THEREOF | 江苏威凯尔医药科技有限公司 | 2024-08-22 | — | — | WO | disclosed |
| CN-118515673-A | BTK inhibitor and application thereof | 江苏威凯尔医药科技有限公司 | 2024-08-20 | — | — | CN | disclosed |
| CN-116947856-A | EZH2 inhibitor and preparation method and application thereof | 星希尔生物科技(上海)有限公司 | 2023-10-27 | — | — | CN | disclosed |