Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 2/20 | 0.56 |
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24653520 | 1.00 | HTR3A (0.56) | HTR3AHRH4HRH3 | |
| SCHEMBL14938526 | 0.86 | HTR3A (0.53) | HTR3AHRH4HRH3 | |
| SCHEMBL29464176 | 0.86 | HTR3A (0.53) | HTR3AHRH4HRH3 | |
| SCHEMBL17222798 | 0.84 | HTR3A (0.51) | HTR3AHRH4HRH3 | |
| SCHEMBL21262025 | 0.84 | HTR3A (0.51) | HTR3AHRH4HRH3 | |
| SCHEMBL4254436 | 0.84 | HTR3A (0.51) | HTR3AHRH4HRH3 | |
| SCHEMBL15544107 | 0.82 | CNR2 (0.41) | HTR3AHRH4 | |
| SCHEMBL30280743 | 0.82 | CNR2 (0.44) | HRH4 | |
| SCHEMBL12488177 | 0.82 | CNR2 (0.44) | HRH4 | |
| SCHEMBL22652074 | 0.82 | HTR3A (0.49) | HTR3AHRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4531838-A1 | IMIDAZOPYRIDINE AND OXAZOLOPYRIDINE DERIVATIVES AND ANALOGS THEREOF, METHODS OF PREPARATION THEREOF, METHODS OF HIF-1/2A PATHWAY INHIBITION, AND INDUCTION OF FERROPTOSIS | Kuda Therapeutics, Inc. (US) | 2025-04-09 | — | — | EP | disclosed |
| WO-2023234970-A1 | IMIDAZOPYRIDINE AND OXAZOLOPYRIDINE DERIVATIVES AND ANALOGS THEREOF, METHODS OF PREPARATION THEREOF, METHODS OF HIF-1/2A PATHWAY INHIBITION, AND INDUCTION OF FERROPTOSIS | KUDA Therapeutics, Inc. (US) | 2023-12-07 | — | — | WO | disclosed |