Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 7/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 4/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CYBB | P04839 | 1/20 | 0.33 |
| ▸ | NOX5 | Q96PH1 | 1/20 | 0.33 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.33 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645256 | 0.92 | MEN1 (0.40) | MEN1KMT2ACSNK1EPOLBCSNK1D | |
| SCHEMBL26645489 | 0.89 | MEN1 (0.44) | MEN1KMT2AGRM5NR1H2POLB | |
| SCHEMBL30622973 | 0.88 | GRM5 (0.41) | MEN1KMT2AGRM5CSNK1ENR1H2 | |
| SCHEMBL30623007 | 0.88 | MEN1 (0.41) | MEN1KMT2AGRM5NR1H2POLB | |
| SCHEMBL30622765 | 0.84 | CSNK1E (0.44) | GRM5CSNK1ECSNK1D | |
| SCHEMBL30623123 | 0.83 | GRM5 (0.43) | GRM5CSNK1ENR1H2CSNK1D | |
| SCHEMBL26645758 | 0.81 | GRM5 (0.43) | MEN1KMT2AGRM5NR1H2POLB | |
| SCHEMBL26645726 | 0.80 | MEN1 (0.46) | MEN1KMT2ACSNK1EPOLBCSNK1D | |
| SCHEMBL26645805 | 0.78 | CSNK1E (0.42) | MEN1KMT2ACSNK1EPOLBCSNK1D | |
| SCHEMBL24277111 | 0.78 | CSNK1E (0.41) | CSNK1ECSNK1DESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |