Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.43 |
| ▸ | CSNK1E | P49674 | 8/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 7/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | ABL2 | P42684 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645271 | 0.92 | CSNK1E (0.46) | CSNK1ECSNK1DUSP30MGAT2DGAT2 | |
| SCHEMBL26645772 | 0.89 | GRM5 (0.51) | GRM5USP30MGAT2DGAT2ABL1 | |
| SCHEMBL30622773 | 0.83 | MEN1 (0.37) | GRM5CSNK1ECSNK1DNR1H2 | |
| SCHEMBL30622973 | 0.83 | GRM5 (0.41) | GRM5CSNK1ENR1H2 | |
| SCHEMBL30622765 | 0.83 | CSNK1E (0.44) | GRM5CSNK1ECSNK1D | |
| SCHEMBL26645904 | 0.80 | CSNK1E (0.55) | CSNK1ECSNK1D | |
| SCHEMBL30622835 | 0.79 | CSNK1E (0.44) | CSNK1ECSNK1DUSP30DGAT2ABL1 | |
| SCHEMBL26645379 | 0.79 | CSNK1E (0.44) | CSNK1ECSNK1DUSP30DGAT2ABL1 | |
| SCHEMBL26645030 | 0.79 | HTT (0.55) | GRM5HTTHDAC6KDM4EMAPT | |
| SCHEMBL16711195 | 0.77 | GRM5 (0.50) | GRM5CSNK1ECSNK1DNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |