Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622818 | 1.00 | SETD7 (0.34) | SETD7MAP4K4GPR119HDAC1HSD11B1 | |
| SCHEMBL26645349 | 1.00 | SETD7 (0.34) | SETD7MAP4K4GPR119HDAC1HSD11B1 | |
| SCHEMBL26645369 | 0.82 | — | — | |
| SCHEMBL26645043 | 0.82 | — | — | |
| SCHEMBL26645373 | 0.82 | — | — | |
| SCHEMBL16697373 | 0.80 | MAP4K4 (0.35) | SETD7MAP4K4GPR119HDAC1HSD11B1 | |
| SCHEMBL30622940 | 0.79 | CSNK1D (0.37) | SETD7MAP4K4HDAC1 | |
| SCHEMBL30622953 | 0.79 | KCNK3 (0.42) | SETD7MEN1KMT2A | |
| SCHEMBL30622815 | 0.79 | CSNK1D (0.37) | SETD7MAP4K4HDAC1 | |
| SCHEMBL30622869 | 0.79 | USP30 (0.39) | SETD7MAP4K4GPR119HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |