Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 6/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
| ▸ | CSNK1E | P49674 | 4/20 | 0.43 |
| ▸ | JAK1 | P23458 | 4/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 4/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645620 | 1.00 | CSNK1D (0.46) | CSNK1DMAPK14MAPK11CSNK1EJAK1 | |
| SCHEMBL30622774 | 0.95 | CSNK1D (0.43) | CSNK1DMAPK14MAPK11CSNK1EJAK1 | |
| SCHEMBL24547959 | 0.88 | CSNK1D (0.50) | CSNK1DMAPK14MAPK11CSNK1EEGFR | |
| SCHEMBL29993957 | 0.88 | CSNK1D (0.50) | CSNK1DMAPK14MAPK11CSNK1EEGFR | |
| SCHEMBL26645860 | 0.86 | CSNK1D (0.41) | CSNK1DMAPK14CSNK1EJAK1CDK9 | |
| SCHEMBL26645523 | 0.85 | CSNK1E (0.42) | CSNK1DCSNK1EGRIA1CDK9CCNT1 | |
| SCHEMBL30622795 | 0.85 | CSNK1E (0.42) | CSNK1DCSNK1EGRIA1CDK9CCNT1 | |
| SCHEMBL30623067 | 0.85 | JAK1 (0.43) | CSNK1DMAPK14JAK1JAK2TYK2 | |
| SCHEMBL26645007 | 0.85 | JAK1 (0.43) | CSNK1DMAPK14JAK1JAK2TYK2 | |
| SCHEMBL26644979 | 0.85 | CSNK1D (0.49) | CSNK1DMAPK14MAPK11CSNK1EJAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |