Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.69 |
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | IDE | P14735 | 1/20 | 0.69 |
| ▸ | MPI | P34949 | 1/20 | 0.69 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.69 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.69 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.59 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.59 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.59 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.59 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.59 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.59 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.59 |
| ▸ | DAO | P14920 | 1/20 | 0.58 |
| ▸ | DDO | Q99489 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9715631 | 1.00 | KDM4E (0.69) | KDM4EALDH1A1MAPTIDEMPI | |
| Hydrochloric Acid SCHEMBL11767787 | 0.98 | KDM4E (0.67) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL1884123 | 0.82 | KDM4E (1.00) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL6343134 | 0.82 | KDM4E (0.62) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL8678798 | 0.78 | KDM4E (0.74) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL29505902 | 0.77 | DAO (0.73) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL13847310 | 0.77 | DAO (0.62) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL2726546 | 0.77 | DAO (0.73) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL14969232 | 0.77 | KDM4E (0.69) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL1228041 | 0.77 | KDM4E (0.62) | KDM4EALDH1A1MAPTIDEMPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260028355-A1 | PROTEOLYSIS TARGETING CHIMERA (PROTAC) COMPOSITIONS USING UBIQUITIN CONJUGATING ENZYME LIGANDS | BERG, KARA ANN | 2026-01-29 | — | — | US | disclosed |
| CN-119546341-A | Proteolytic targeting chimeric (PROTAC) compositions using ubiquitin conjugated enzyme ligands | 布普格生物制药公司 | 2025-02-28 | — | — | CN | disclosed |
| EP-4429705-A1 | PROTEOLYSIS TARGETING CHIMERA (PROTAC) COMPOSITIONS USING UBIQUITIN CONJUGATING ENZYME LIGANDS | Berg LLC (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023205219-A1 | PROTEOLYSIS TARGETING CHIMERA (PROTAC) COMPOSITIONS USING UBIQUITIN CONJUGATING ENZYME LIGANDS | BERG LLC (US) | 2023-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260028355-A1 | PROTEOLYSIS TARGETING CHIMERA (PROTAC) COMPOSITIONS USING UBIQUITIN CONJUGATING ENZYME LIGANDS | UBE2T, UBE3C, UBE2E1 | KDM4E 1637/4885ALDH1A1 3389/4885MAPT 468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.