Sugi Predict
/ Targets
/ UBE2E1
Top predicted compounds (top 20 by supporting neighbours, then confidence)
Clinical trials — most relevant to UBE2E1 by text similarity (a relevance ranking, not an exhaustive list)
| Trial | Phase | Status |
|---|
| A Study Evaluating the Efficacy and Safety of Momelotinib in Participants With Vacuoles, E1-enzyme, X-linked, Autoinflammatory, Somatic (VEXAS) Syndrome |
PHASE2/PHASE3 | NOT_YET_RECRUITING |
| Phase 3 Efficacy and Safety Study of GTX-102 in Pediatric Subjects With Angelman Syndrome (AS) |
PHASE3 | ACTIVE_NOT_RECRUITING |
| Study to Compare the Safety and Efficacy of UB-851 and Eprex® |
PHASE3 | COMPLETED |
| Platform Trial to Compare Homologous Boost of Authorized COVID-19 Vaccines and Heterologous Boost With UB-612 Vaccine |
PHASE3 | UNKNOWN |
| To Investigate the Efficacy and Safety of UB-421 Monotherapy in HIV-1 Infected Adults |
PHASE3 | WITHDRAWN |
| A Study of UBT251 in Participants With Metabolic Dysfunction-Associated Steatohepatitis (MASH) |
PHASE2 | RECRUITING |
| Alrizomadlin (APG-115) in Subjects With BAP1 Cancer Syndrome and Early-Stage Mesothelioma |
PHASE2 | WITHDRAWN |
| A Trial of Anti-CD4 Antibody UB-421 in Combination With Optimized Background Antiretroviral Therapy in Patients With Multi-Drug Resistant HIV-1 Infection |
PHASE2 | WITHDRAWN |
| Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesothelioma |
PHASE2 | SUSPENDED |
| Testing the Combination of MLN4924 (Pevonedistat), Carboplatin, and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) Who Have Previously Been Treated With Immunotherapy |
PHASE2 | ACTIVE_NOT_RECRUITING |
| Phase II Prospective Cohort Study of Intravesical Recombinant Human Type 5 Adenovirus Injection for Treatment of High-Risk Non-Muscle Invasive Bladder Cancer: Evaluating Efficacy and Safety |
PHASE2 | NOT_YET_RECRUITING |
| Desferal Administration to Improve the Impaired Reaction to Hypoxia in Diabetes |
PHASE2 | UNKNOWN |
| Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers |
PHASE2 | NOT_YET_RECRUITING |
| A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of RO7248824 in Participants With Angelman Syndrome (AS) |
PHASE1 | COMPLETED |
| A Extension Study to Evaluate the Safety, Tolerability, and Immunogenicity of UB-612 COVID-19 Vaccine |
PHASE1 | COMPLETED |
| PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck |
PHASE1 | COMPLETED |
| Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis |
nan | UNKNOWN |
| Prognostic Value of Combined Approach Based on KEAP1/NFE2L2 Mutations and Pre-therapeutic FDG-PET/CT Radiomic Analysis in Advanced Non-small-cell Lung Cancer PDL1 ≥ 50% Treated With Pembrolizumab (PEMBROMIC) |
nan | UNKNOWN |
| A Natural History Study of Angelman Syndrome |
nan | RECRUITING |
| Biomarkers in Tumor Samples From Younger Patients With Neuroblastoma |
nan | COMPLETED |
| Long Term Follow-Up of Patients With Mesothelioma and Individuals With Germline Mutations in BAP1 |
nan | RECRUITING |
| Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome |
nan | RECRUITING |
| Clinical Study of 68Ga-DOTA-BLP PET Imaging in Noninvasive Diagnosis of Malignant Tumors |
nan | NOT_YET_RECRUITING |
| The Role of RING Ubiquitin Ligases in Biologic and Oncologic Processes in Tissues of Mesenchymal Origin |
nan | UNKNOWN |
| HRQoL and Financial Toxicity in Patients With VEXAS Syndrome |
nan | RECRUITING |
| Male breAsT cAncer preDisposition Factor: Creation of a Control Cohort 2 |
nan | NOT_YET_RECRUITING |
| Low Dose Melphalan and Bortezomib for AML and High-Risk MDS |
nan | COMPLETED |
| Inhibition of SENP1 for the Suppression of OS Growth and Metastasis |
nan | UNKNOWN |
| Endocrine Disruptors and Life STILe in Breast Cancer Development |
nan | UNKNOWN |
| Establishment of a Prospective Clinical-biological Database |
nan | RECRUITING |
Related proteins — ESM-2 sequence neighbours (a UBE2E1 binder may also engage these)