Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | RPA1 | P27694 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26074934 | 1.00 | KDM4E (0.42) | KDM4EABCB1RARGSCN9AALOX15 | |
| SCHEMBL30626334 | 0.89 | CYP1A2 (0.45) | KDM4EABCB1RARGALOX15HSD17B10 | |
| SCHEMBL26074925 | 0.89 | CYP1A2 (0.45) | KDM4EABCB1RARGALOX15HSD17B10 | |
| SCHEMBL26075498 | 0.89 | KDM4E (0.46) | KDM4ERARGALOX15HSD17B10ALDH1A1 | |
| SCHEMBL26074959 | 0.88 | KDM4E (0.40) | KDM4EHSD17B10ALDH1A1NPSR1TP53 | |
| SCHEMBL30626340 | 0.88 | KDM4E (0.40) | KDM4EHSD17B10ALDH1A1NPSR1TP53 | |
| SCHEMBL30626339 | 0.86 | KDM4E (0.41) | KDM4ERARGSCN9AALOX15HSD17B10 | |
| SCHEMBL30626350 | 0.86 | SCN9A (0.41) | KDM4ESCN9AALDH1A1HPGDNPSR1 | |
| SCHEMBL26075507 | 0.86 | KDM4E (0.39) | KDM4ERARGSCN9AALOX15HSD17B10 | |
| SCHEMBL26074932 | 0.86 | SCN9A (0.41) | KDM4ESCN9AALDH1A1HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303498-A1 | HERBICIDAL CINNOLINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2023-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303498-A1 | HERBICIDAL CINNOLINE DERIVATIVES | DDT, DERL1, MTX1 | KDM4E 2666/4885ABCB1 501/4885RARG 4208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.