Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.56 |
| ▸ | RAF1 | P04049 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29114185 | 1.00 | HPGD (0.56) | HPGDALDH1A1CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL29149160 | 0.92 | HPGD (0.55) | HPGDALDH1A1CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL30626958 | 0.84 | HPGD (0.46) | HPGDALDH1A1CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL29114161 | 0.83 | AKR1C3 (0.58) | HPGDALDH1A1CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL30626957 | 0.83 | AKR1C3 (0.58) | HPGDALDH1A1CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL30626959 | 0.82 | LCK (0.72) | HPGDALDH1A1CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL29149144 | 0.81 | LCK (0.65) | HPGDALDH1A1CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL29114159 | 0.78 | AKR1C3 (0.56) | HPGDALDH1A1CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL30626963 | 0.78 | AKR1C3 (0.56) | HPGDALDH1A1CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL253522 | 0.77 | HPGD (0.78) | HPGDALDH1A1CYP3A4MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947799-A | Phenolic compound, preparation method and medical application thereof | 上海泽德曼医药科技有限公司 | 2023-10-27 | — | — | CN | disclosed |