Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.78 |
| ▸ | MAPT | P10636 | 6/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.78 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.78 |
| ▸ | MEN1 | O00255 | 5/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.78 |
| ▸ | RAB9A | P51151 | 4/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.78 |
| ▸ | TSHR | P16473 | 3/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.78 |
| ▸ | NPC1 | O15118 | 3/20 | 0.78 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.78 |
| ▸ | TP53 | P04637 | 3/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.78 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.78 |
| ▸ | GMNN | O75496 | 1/20 | 0.78 |
| ▸ | RAF1 | P04049 | 1/20 | 0.78 |
| ▸ | PKM | P14618 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649187 | 0.89 | HPGD (0.74) | HPGDCYP3A4ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29504929 | 0.88 | HPGD (1.00) | HPGDCYP3A4ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL157826 | 0.88 | HPGD (1.00) | HPGDCYP3A4ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11289655 | 0.88 | HPGD (0.73) | HPGDCYP3A4ALDH1A1MAPTSMN1; SMN2 | |
| Water SCHEMBL8404969 | 0.86 | HPGD (0.97) | HPGDCYP3A4ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30089725 | 0.86 | AR (0.72) | HPGDCYP3A4ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30660103 | 0.86 | AR (1.00) | HPGDCYP3A4ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4649397 | 0.86 | AR (0.72) | HPGDCYP3A4ALDH1A1MAPTSMN1; SMN2 | |
| 7,2'-Dimethoxyflavone SCHEMBL4285153 | 0.86 | AR (0.81) | HPGDCYP3A4ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4443406 | 0.86 | AR (1.00) | HPGDCYP3A4ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250282871-A1 | PHARMACEUTICAL COMBINATION AND USE THEREOF | TIANJIN LIPOGEN TECH CO LTD (CN) | 2025-09-11 | — | — | US | claimed |
| US-12239655-B2 | Combined modalities for nucleosides and/or NADPH oxidase (NOX) inhibitors as myeloid-specific antiviral agents | EMORY UNIVERSITY (US) | 2025-03-04 | — | — | US | claimed |
| EP-4384027-A1 | COMPOSITION COMPRISING A NUTRIENT AND A TASTE MODULATOR | Firmenich SA (CH) | 2024-06-19 | — | — | EP | claimed |
| WO-2024114248-A1 | CITRUS FRUIT EXTRACT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 三峡大学 | 2024-06-06 | — | — | WO | claimed |
| EP-4342492-A1 | PHARMACEUTICAL COMBINATION AND USE THEREOF | Tianjin Lipogen Technology Co., Ltd (CN) | 2024-03-27 | — | — | EP | claimed |
| EP-4329499-A1 | FLAVOR-MODIFYING COMPOSITIONS CONTAINING LACTASE | Firmenich SA (CH) | 2024-03-06 | — | — | EP | claimed |
| WO-2023108169-A2 | METHODS AND COMPOSITIONS FOR THE BIOSYNTHESIS AND USE OF DEMETHYLATED POLYMETHOXY FLAVONES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2023-06-15 | — | — | WO | claimed |
| WO-2023072604-A1 | COMPOSITION COMPRISING A NUTRIENT AND A TASTE MODULATOR | FIRMENICH SA (CH) | 2023-05-04 | — | — | WO | claimed |
| CN-115948362-A | Oxygen methyltransferase participating in biosynthesis of polymethoxyflavone in citrus peel, coding gene, amplification primer pair and application | 浙江大学 | 2023-04-11 | — | — | CN | claimed |
| CN-115813991-A | Application of citrus fruit extract in preparation of medicine for treating breast cancer endocrine | 三峡大学 | 2023-03-21 | — | — | CN | claimed |
| US-20020016358-A1 | Cosmetic composition | NOF CORPORATION | 2002-02-07 | — | — | US | claimed |
| US-20020006953-A1 | MODIFICATION OF CHOLESTEROL CONCENTRATIONS WITH CITUS PHYTOCHEMICALS | TROPICANA PRODUCTS, INC. | 2002-01-17 | — | — | US | claimed |
| EP-1147764-A2 | Cosmetic composition | NOF CORPORATION (JP) | 2001-10-24 | — | — | EP | claimed |
| CN-1318366-A | Cosmetics composition | NIPPON OILS & FATS CO LTD (JP) | 2001-10-24 | — | — | CN | claimed |
| WO-2001070029-A1 | COMPOSITIONS AND METHODS OF TREATING, REDUCING, AND PREVENTING CARDIOVASCULAR DISEASES AND DISORDERS WITH POLYMETHOXYFLAVONES | KGK SYNERGIE (CA) | 2001-09-27 | — | — | WO | claimed |
| WO-2001032160-A2 | MODIFICATION OF CHOLESTEROL CONCENTRATIONS WITH CITRUS PHYTOCHEMICALS | TROPICANA PRODUCTS, INC. (US) | 2001-05-10 | — | — | WO | claimed |
| WO-2001021137-A1 | EXTRACTS OF ORANGE PEEL FOR PREVENTION AND TREATMENT OF CANCER | RUTGERS, THE STATE UNIVERSITY (US) | 2001-03-29 | — | — | WO | claimed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | claimed |
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | claimed |
| US-5399584-A | Preventing gastrointestinal damage caused by nonsteroidal antiinflammatory drugs | THE PROCTER & GAMBLE COMPANY (US) | 1995-03-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020016358-A1 | Cosmetic composition | PLIN5, TEAD3, CUTA | HPGD 1414/4885CYP3A4 3800/4885ALDH1A1 3843/4885 |
| US-12239655-B2 | Combined modalities for nucleosides and/or NADPH oxidase (NOX) inhibitors as myeloid-specific antiviral agents | NOX1, NOX3, NOX4 | HPGD 256/4885CYP3A4 1105/4885ALDH1A1 1165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.