Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18384500 | 1.00 | MAPT (0.54) | MAPTKDM4EALDH1A1HPGDHDAC3 | |
| SCHEMBL4801780 | 0.88 | MAPT (0.46) | MAPTKDM4EALDH1A1HPGDHDAC3 | |
| SCHEMBL4416895 | 0.88 | KDM4E (0.46) | MAPTKDM4EALDH1A1HPGDHDAC3 | |
| SCHEMBL9431176 | 0.88 | MAPT (0.49) | MAPTKDM4EALDH1A1HPGDHDAC3 | |
| SCHEMBL18384536 | 0.81 | KDM4E (0.48) | MAPTKDM4EALDH1A1HPGDHDAC3 | |
| SCHEMBL22132935 | 0.80 | CSNK2A2 (0.41) | MAPTKDM4EALDH1A1HPGDHDAC3 | |
| SCHEMBL2895989 | 0.79 | ALDH1A1 (0.55) | MAPTKDM4EALDH1A1HPGDHDAC3 | |
| SCHEMBL17842695 | 0.78 | MAPT (0.56) | MAPTKDM4EALDH1A1HPGDHDAC3 | |
| SCHEMBL17858498 | 0.78 | MAPT (0.56) | MAPTKDM4EALDH1A1HPGDHDAC3 | |
| SCHEMBL4807046 | 0.78 | KDM4E (0.51) | MAPTKDM4EALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947879-A | BBI608 derivative, preparation method thereof and application thereof in preparing medicines for treating STAT3 mediated diseases | 沈阳药科大学 | 2023-10-27 | — | — | CN | disclosed |