Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | MC5R | P33032 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7374803 | 0.87 | PARP1 (0.40) | PARP1ALDH1A1TSHRLMNAMEN1 | |
| SCHEMBL8147630 | 0.83 | MAPT (0.43) | PARP1ALDH1A1LMNAL3MBTL1MAPT | |
| SCHEMBL27868891 | 0.82 | GPR119 (0.45) | PARP1ALDH1A1TSHRLMNAMEN1 | |
| SCHEMBL29773951 | 0.82 | GPR119 (0.45) | PARP1ALDH1A1TSHRLMNAMEN1 | |
| SCHEMBL28112473 | 0.81 | GPR119 (0.46) | PARP1 | |
| SCHEMBL31105123 | 0.81 | PARP1 (0.40) | PARP1ALDH1A1TSHRLMNAMEN1 | |
| SCHEMBL31388549 | 0.80 | PARP1 (0.42) | PARP1ALDH1A1TSHRLMNAMEN1 | |
| SCHEMBL20312846 | 0.80 | GSK3B (0.37) | PARP1MEN1KMT2A | |
| SCHEMBL29757596 | 0.80 | GPR119 (0.45) | PARP1 | |
| SCHEMBL28412863 | 0.80 | GPR119 (0.45) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116867758-A | IRAK degradation agents and uses thereof | 凯麦拉医疗公司 | 2023-10-10 | — | — | CN | disclosed |