Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | CKS1B | P61024 | 1/20 | 0.33 |
| ▸ | SKP1 | P63208 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30628519 | 0.90 | EIF2AK4 (0.42) | EIF2AK4AURKAPDPK1AURKBBTK | |
| SCHEMBL30628510 | 0.89 | EIF2AK4 (0.45) | EIF2AK4AURKAPDPK1AURKBBTK | |
| SCHEMBL30628509 | 0.88 | EIF2AK4 (0.41) | EIF2AK4AURKAPDPK1AURKBBTK | |
| SCHEMBL30628495 | 0.87 | EIF2AK4 (0.41) | EIF2AK4AURKAPDPK1AURKBBTK | |
| SCHEMBL26632113 | 0.86 | ALDH1A1 (0.36) | KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL26758703 | 0.85 | AURKA (0.46) | EIF2AK4AURKAPDPK1AURKBBTK | |
| SCHEMBL30628535 | 0.85 | AURKA (0.46) | EIF2AK4AURKAPDPK1AURKBBTK | |
| SCHEMBL30628500 | 0.84 | EIF2AK4 (0.44) | EIF2AK4AURKAPDPK1AURKBBTK | |
| SCHEMBL16608976 | 0.84 | CKS1B (0.45) | BTKJAK3SUV39H2DRD2CKS1B | |
| SCHEMBL11912147 | 0.82 | EIF2AK4 (0.46) | EIF2AK4AURKAPDPK1AURKBDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023211256-A1 | NOVEL PIM KINASE INHIBITORS AND USES THEREOF | 제일약품주식회사 | 2023-11-02 | — | — | WO | disclosed |