Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 5/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 2/20 | 0.30 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26630200 | 1.00 | PDK1 (0.34) | PDK1HSP90AA1HSP90AB1BRD4HSD17B10 | |
| SCHEMBL21000380 | 0.81 | BRD4 (0.33) | PDK1HSP90AA1HSP90AB1BRD4GSK3B | |
| SCHEMBL12599212 | 0.80 | BRD4 (0.36) | PDK1HSP90AA1HSP90AB1BRD4GSK3B | |
| SCHEMBL31370721 | 0.80 | BRD4 (0.35) | PDK1HSP90AA1HSP90AB1BRD4HSD17B10 | |
| SCHEMBL24330125 | 0.79 | PDK1 (0.36) | PDK1BRD4HSD17B10GSK3BMAP3K5 | |
| SCHEMBL30731040 | 0.79 | HSD17B10 (0.42) | PDK1HSP90AA1HSP90AB1BRD4HSD17B10 | |
| SCHEMBL30611189 | 0.79 | PDK1 (0.36) | PDK1BRD4HSD17B10GSK3BMAP3K5 | |
| SCHEMBL15384517 | 0.79 | HSD17B10 (0.42) | PDK1HSP90AA1HSP90AB1BRD4HSD17B10 | |
| SCHEMBL31513446 | 0.79 | BRD4 (0.50) | BRD4GSK3BADORA2AADORA1 | |
| SCHEMBL22554076 | 0.79 | BRD4 (0.50) | BRD4GSK3BADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4514780-A1 | BICYCLE COMPOUNDS AS TEAD INHIBITOR | Dong-A ST Co., Ltd. (KR) | 2025-03-05 | — | — | EP | disclosed |
| WO-2023209651-A1 | BICYCLE COMPOUNDS AS TEAD INHIBITOR | DONG-A ST CO., LTD. (KR) | 2023-11-02 | — | — | WO | disclosed |