SCHEMBL30628958

SCHEMBL30628958

CC(C)(C)OC(=O)/C=C/c1cnc2ccc(Br)cc2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
KDM4E B2RXH2 2/20 0.52
RAB9A P51151 3/20 0.44
MET P08581 5/20 0.39
KDR P35968 2/20 0.38
AURKA O14965 1/20 0.38
ABL1 P00519 1/20 0.38
LCK P06239 1/20 0.38
FYN P06241 1/20 0.38
YES1 P07947 1/20 0.38
FGFR2 P21802 1/20 0.38
EPHA2 P29317 1/20 0.38
LTK P29376 1/20 0.38
AXL P30530 1/20 0.38
FLT3 P36888 1/20 0.38
MST1R Q04912 1/20 0.38
PTK6 Q13882 1/20 0.38
MALT1 Q9UDY8 1/20 0.38
ALDH1A1 P00352 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26750756 1.00 KMT2A (0.52) KMT2ASMN1; SMN2KDM4ERAB9AMET
SCHEMBL26750753 0.86 KDM4E (0.53) KMT2ASMN1; SMN2KDM4ERAB9AMET
SCHEMBL9751 0.86 KDM4E (0.70) KMT2ASMN1; SMN2KDM4ERAB9AMET
SCHEMBL9752 0.86 KDM4E (0.70) KMT2ASMN1; SMN2KDM4ERAB9AMET
SCHEMBL30487516 0.84 KDM4E (0.74) KMT2ASMN1; SMN2KDM4ERAB9AALDH1A1
SCHEMBL6070391 0.84 KDM4E (0.74) KMT2ASMN1; SMN2KDM4ERAB9AALDH1A1
SCHEMBL29733054 0.84 KDM4E (0.74) KMT2ASMN1; SMN2KDM4ERAB9AALDH1A1
SCHEMBL6070393 0.84 KDM4E (0.74) KMT2ASMN1; SMN2KDM4ERAB9AALDH1A1
SCHEMBL30628952 0.82 PTPN1 (0.48) KMT2ASMN1; SMN2RAB9AMEN1NPC1
SCHEMBL26750709 0.82 PTPN1 (0.48) KMT2ASMN1; SMN2RAB9AMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4519384-B1 PHOTOACTIVATABLE COMPOUNDS AND USES THEREOF PROMEGA CORP (US) 2026-04-29 EP disclosed
EP-4519384-A1 PHOTOACTIVATABLE COMPOUNDS AND USES THEREOF Promega Corporation (US) 2025-03-12 EP disclosed
EP-4519385-A2 BIOLUMINESCENCE-TRIGGERED PHOTOCATALYTIC LABELING PROMEGA CORPORATION (US) 2025-03-12 EP disclosed
US-20240191211-A1 BIOLUMINESCENCE-TRIGGERED PHOTOCATALYTIC LABELING PROMEGA CORPORATION 2024-06-13 US disclosed
WO-2023215497-A1 PHOTOACTIVATABLE COMPOUNDS AND USES THEREOF PROMEGA CORPORATION (US) 2023-11-09 WO disclosed
WO-2023215514-A2 BIOLUMINESCENCE-TRIGGERED PHOTOCATALYTIC LABELING PROMEGA CORPORATION (US) 2023-11-09 WO disclosed
US-20230357266-A1 PHOTOACTIVATABLE COMPOUNDS AND USES THEREOF PROMEGA CORPORATION 2023-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357266-A1 PHOTOACTIVATABLE COMPOUNDS AND USES THEREOF BTD, HLCS, TYR KMT2A 2293/4885SMN1; SMN2 4845/4885KDM4E 1476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.