Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | NPY2R | P49146 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30629068 | 1.00 | MAPT (0.37) | MAPTALDH1A1GAAMEN1HPGD | |
| SCHEMBL26110394 | 1.00 | MAPT (0.37) | MAPTALDH1A1GAAMEN1HPGD | |
| SCHEMBL30629033 | 0.86 | MEN1 (0.37) | MAPTALDH1A1GAAMEN1HPGD | |
| SCHEMBL26108155 | 0.86 | MEN1 (0.37) | MAPTALDH1A1GAAMEN1HPGD | |
| SCHEMBL30629044 | 0.85 | MAPT (0.38) | MAPTALDH1A1GAAMEN1HPGD | |
| SCHEMBL26109423 | 0.85 | MAPT (0.38) | MAPTALDH1A1GAAMEN1HPGD | |
| SCHEMBL26105819 | 0.82 | HSD11B1 (0.41) | MAPTALDH1A1GAAMEN1HPGD | |
| SCHEMBL30629095 | 0.82 | MEN1 (0.37) | MAPTALDH1A1GAAMEN1HPGD | |
| SCHEMBL26107631 | 0.82 | MEN1 (0.37) | MAPTALDH1A1GAAMEN1HPGD | |
| SCHEMBL29082554 | 0.77 | MEN1 (0.41) | MAPTALDH1A1GAAMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836157-A | Oxadiazole derivative and preparation method and application thereof | 星希尔生物科技(上海)有限公司 | 2023-10-03 | — | — | CN | disclosed |