Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21801155 | 1.00 | SIGMAR1 (0.41) | SIGMAR1CYSLTR1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL21801157 | 1.00 | SIGMAR1 (0.41) | SIGMAR1CYSLTR1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL30744085 | 0.92 | SIGMAR1 (0.39) | SIGMAR1CYSLTR1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL21801145 | 0.92 | SIGMAR1 (0.39) | SIGMAR1CYSLTR1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL21801211 | 0.92 | SIGMAR1 (0.39) | SIGMAR1 | |
| SCHEMBL21801217 | 0.92 | SIGMAR1 (0.39) | SIGMAR1CYSLTR1 | |
| SCHEMBL21801254 | 0.92 | SIGMAR1 (0.39) | SIGMAR1CYSLTR1 | |
| SCHEMBL21801142 | 0.92 | SIGMAR1 (0.39) | SIGMAR1CYSLTR1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL22231164 | 0.91 | ABCB1 (0.46) | SIGMAR1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL21801184 | 0.91 | SIGMAR1 (0.40) | SIGMAR1CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112601743-B | Flavone compounds for the treatment and prevention of hepatitis b virus diseases | 豪夫迈·罗氏有限公司 | 2023-12-19 | — | — | CN | claimed |
| CN-112601743-B | Flavone compounds for the treatment and prevention of hepatitis b virus diseases | 豪夫迈·罗氏有限公司 | 2023-12-19 | — | — | CN | disclosed |
| EP-3849966-B1 | FLAVONE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS DISEASE | HOFFMANN LA ROCHE (CH) | 2023-10-25 | — | — | EP | disclosed |