Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PRKCH | P24723 | 7/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 7/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 6/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 6/20 | 0.36 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 3/20 | 0.34 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.32 |
| ▸ | PKN1 | Q16512 | 2/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | PRKCB | P05771 | 2/20 | 0.32 |
| ▸ | PRKCA | P17252 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30630186 | 0.75 | GRM2 (0.40) | MAPTNPC1PRKCDNFATC1GSK3B | |
| SCHEMBL13735414 | 0.72 | MAPK14 (0.50) | MAPTNPC1 | |
| SCHEMBL22075846 | 0.71 | DGAT1 (0.39) | MAPTNPC1KDM4E | |
| SCHEMBL22075678 | 0.69 | CYP11B1 (0.43) | MAPTNFATC1GSK3BDYRK1A | |
| SCHEMBL6486659 | 0.68 | NTRK1 (0.51) | MAPTNPC1CYP1A2KDM4ENTRK1 | |
| SCHEMBL28540172 | 0.68 | MAPT (0.58) | MAPTCYP1A2 | |
| SCHEMBL10364947 | 0.67 | NTRK1 (0.42) | MAPTNPC1CYP1A2KDM4ENTRK1 | |
| SCHEMBL17967620 | 0.67 | MAPT (0.63) | MAPTNPC1NFATC1GSK3BDYRK1A | |
| SCHEMBL29094472 | 0.66 | HDAC8 (0.38) | MAPTNPC1NFATC1GSK3BDYRK1A | |
| SCHEMBL31410649 | 0.66 | DGAT1 (0.37) | MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120090-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2023-11-24 | — | — | CN | disclosed |