Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.36 |
| ▸ | MC4R | P32245 | 4/20 | 0.35 |
| ▸ | GPR183 | P32249 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.33 |
| ▸ | KDM5A | P29375 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 4/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | SMO | Q99835 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24424352 | 1.00 | ACACB (0.36) | ACACBMC4RGPR183LRRK2KDM5A | |
| SCHEMBL24424639 | 0.91 | ACACB (0.37) | ACACBMC4RGPR183LRRK2KDM5A | |
| SCHEMBL24424425 | 0.85 | NPC1 (0.42) | MEN1ALDH1A1KMT2A | |
| SCHEMBL24422999 | 0.82 | POLB (0.44) | EPHX2 | |
| SCHEMBL29583762 | 0.82 | POLB (0.44) | EPHX2 | |
| SCHEMBL29585960 | 0.81 | SMO (0.44) | KDM5ASMOMEN1ALDH1A1KMT2A | |
| SCHEMBL29243339 | 0.81 | SMO (0.44) | KDM5ASMOMEN1ALDH1A1KMT2A | |
| SCHEMBL24423866 | 0.81 | GAA (0.40) | KDM5ASMOALDH1A1KMT2A | |
| SCHEMBL30298763 | 0.80 | KDM5A (0.39) | KDM5ASMOMEN1ALDH1A1KMT2A | |
| SCHEMBL24423782 | 0.80 | ALDH1A1 (0.41) | KDM5AMEN1ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116635380-A | PPARgamma modulators and methods of use | 卫材R&D管理有限公司 | 2023-08-22 | — | — | CN | disclosed |