Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 9/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.33 |
| ▸ | CDK2 | P24941 | 3/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.31 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24424032 | 1.00 | CHRM4 (0.35) | CHRM4CCNE1CDK2SMOFFAR2 | |
| SCHEMBL24423040 | 0.91 | FFAR2 (0.35) | CHRM4CCNE1CDK2SMOFFAR2 | |
| SCHEMBL29585588 | 0.90 | CHRM4 (0.34) | CHRM4SMOFFAR2GRM4NPC1 | |
| SCHEMBL30630805 | 0.90 | CHRM4 (0.34) | CHRM4SMOFFAR2GRM4NPC1 | |
| SCHEMBL24423446 | 0.90 | CHRM4 (0.34) | CHRM4SMOFFAR2GRM4NPC1 | |
| SCHEMBL24424150 | 0.82 | POLB (0.44) | — | |
| SCHEMBL29583332 | 0.82 | POLB (0.44) | — | |
| SCHEMBL24422937 | 0.82 | TDP1 (0.32) | CHRM4 | |
| SCHEMBL24423713 | 0.81 | CYP4F2 (0.36) | CHRM4SMOFFAR2 | |
| SCHEMBL29584640 | 0.81 | CYP4F2 (0.36) | CHRM4SMOFFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116635380-A | PPARgamma modulators and methods of use | 卫材R&D管理有限公司 | 2023-08-22 | — | — | CN | disclosed |