Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30631218 | 0.84 | ALDH1A1 (0.45) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30631210 | 0.81 | ALDH1A1 (0.44) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30631205 | 0.81 | ALDH1A1 (0.44) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12510329 | 0.79 | ALDH1A1 (0.51) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30631192 | 0.76 | MAPT (0.49) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12824218 | 0.75 | ALDH1A1 (0.46) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11914745 | 0.75 | ALDH1A1 (0.46) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16686924 | 0.72 | ALDH1A1 (0.46) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL38661608 | 0.72 | SCN5A (0.51) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16686955 | 0.72 | MAPT (0.43) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116987076-A | 1,2, 4-triazolo [4,3-a ] pyridine sulfone derivative, and preparation method and application thereof | 贵州大学 | 2023-11-03 | — | — | CN | disclosed |