Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 3/20 | 0.59 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.59 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.48 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32667946 | 0.78 | PDGFRB (0.77) | PDGFRBPDGFRACYP2A6RAB9ANISCH | |
| SCHEMBL2772360 | 0.78 | PDGFRB (0.77) | PDGFRBPDGFRACYP2A6RAB9ANISCH | |
| SCHEMBL572750 | 0.77 | PDPK1 (0.60) | PDPK1CYP2A6RAB9ACYP1A2NPC1 | |
| 2-Phenylthiazole SCHEMBL27609000 | 0.77 | PDPK1 (0.70) | PDPK1CYP2A6RAB9ANPC1POLB | |
| SCHEMBL19180724 | 0.75 | PDGFRB (1.00) | PDGFRBPDGFRACYP2A6BIRC5PIK3CD | |
| SCHEMBL29375041 | 0.75 | PDGFRB (0.60) | PDGFRBPDGFRACYP2A6RAB9ANISCH | |
| SCHEMBL27651543 | 0.75 | PDGFRB (0.60) | PDGFRBPDGFRACYP2A6RAB9ANISCH | |
| SCHEMBL29033356 | 0.74 | PDGFRB (0.53) | PDGFRBPDGFRACYP2A6NISCHBIRC5 | |
| SCHEMBL27631123 | 0.73 | PDGFRB (0.51) | PDGFRBPDGFRACYP2A6NISCHBIRC5 | |
| SCHEMBL24412080 | 0.73 | PDGFRB (0.65) | PDGFRBPDGFRACYP2A6RAB9ANISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016045127-A1 | INHIBITORS OF HIF PROLYL HYDROXYLASE | MERCK SHARP & DOHME CORP. (US) | 2016-03-31 | — | — | WO | disclosed |
| US-20100267697-A1 | ION CHANNEL MODULATORS | WYETH (US) | 2010-10-21 | — | — | US | disclosed |
| CN-100443483-C | Condensed ring unit terminated oligomerized thiophen analog high mobility organic semi-conducting material and its uses | CHANGCHUN APPLIED CHEMISTRY (CN) | 2008-12-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267697-A1 | ION CHANNEL MODULATORS | CACNA1E, CACNA1A, CACNA1S | PDGFRB 3003/4885PDGFRA 2121/4885PDPK1 1902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.