Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 16/20 | 0.45 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
| ▸ | ITGAL | P20701 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22816391 | 1.00 | HAO1 (0.45) | HAO1ITGB2ICAM1ITGALKAT6A | |
| SCHEMBL22817013 | 0.99 | HAO1 (0.44) | HAO1ITGB2ICAM1ITGALKAT6A | |
| SCHEMBL30631949 | 0.99 | HAO1 (0.44) | HAO1ITGB2ICAM1ITGALKAT6A | |
| Trifluoroacetic Acid SCHEMBL22608635 | 0.94 | HAO1 (0.41) | HAO1ITGB2ICAM1ITGAL | |
| Trifluoroacetic Acid SCHEMBL22608395 | 0.93 | HAO1 (0.40) | HAO1ITGB2ICAM1ITGAL | |
| SCHEMBL22816389 | 0.86 | TUBB4A (0.44) | HAO1ITGB2ICAM1ITGALMAOB | |
| SCHEMBL22817014 | 0.85 | TUBB4A (0.45) | HAO1ITGB2ICAM1ITGALMAOB | |
| SCHEMBL22608636 | 0.84 | ITGB2 (0.40) | HAO1ITGB2ICAM1ITGALMEN1 | |
| SCHEMBL22608396 | 0.83 | ITGB2 (0.39) | HAO1ITGB2ICAM1ITGALKAT6A | |
| SCHEMBL22608082 | 0.79 | HAO1 (0.66) | HAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117126151-A | Glycolate oxidase inhibitors for use in the treatment of disease | 生物马林药物股份有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-117069713-A | Glycolate oxidase inhibitors for use in the treatment of disease | 生物马林药物股份有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-117069712-A | Glycolate oxidase inhibitors for use in the treatment of disease | 生物马林药物股份有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-117024420-A | Glycolate oxidase inhibitors for use in the treatment of disease | 生物马林药物股份有限公司 | 2023-11-10 | — | — | CN | disclosed |