Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30632335 | 0.85 | KDM4E (0.56) | NPSR1ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL30632417 | 0.82 | SMN1; SMN2 (0.51) | NPSR1ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL29923275 | 0.81 | MAPT (0.63) | NPSR1ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL12896373 | 0.81 | MAPT (0.63) | NPSR1ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL13658471 | 0.81 | HDAC8 (0.68) | NPSR1ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL30632355 | 0.81 | HDAC8 (0.68) | NPSR1ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL9935900 | 0.81 | ALDH1A1 (0.75) | NPSR1ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL22388821 | 0.80 | KDM4E (0.71) | NPSR1ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL29389712 | 0.80 | KDM4E (0.71) | NPSR1ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL29831664 | 0.80 | CA12 (0.66) | NPSR1ALDH1A1KDM4EMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024327-A | Isoindolinone-based derivative, and preparation method and application thereof | 华东理工大学 | 2023-11-10 | — | — | CN | disclosed |