Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TACR3 | P29371 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.31 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26685076 | 1.00 | MAPT (0.34) | MAPTTACR3THRBSMARCA2SMARCA4 | |
| SCHEMBL31582429 | 0.91 | — | — | |
| SCHEMBL26888967 | 0.91 | MAPT (0.37) | MAPTTACR3THRBSMARCA2SMARCA4 | |
| SCHEMBL31294046 | 0.87 | MAPT (0.35) | MAPTTACR3THRBSMARCA2SMARCA4 | |
| SCHEMBL26685198 | 0.86 | SMARCA2 (0.38) | TACR3SMARCA2SMARCA4LRRK2 | |
| SCHEMBL30632465 | 0.86 | SMARCA2 (0.38) | TACR3SMARCA2SMARCA4LRRK2 | |
| SCHEMBL26684978 | 0.86 | TACR3 (0.38) | TACR3SMARCA2SMARCA4 | |
| SCHEMBL30632503 | 0.86 | TACR3 (0.38) | TACR3SMARCA2SMARCA4 | |
| SCHEMBL31293898 | 0.84 | MAPT (0.33) | MAPTTACR3THRBSMARCA2SMARCA4 | |
| SCHEMBL30632443 | 0.82 | MAPT (0.33) | MAPTTACR3THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119998278-A | Compounds and uses thereof | 福宏治疗公司 | 2025-05-13 | — | — | CN | disclosed |
| EP-4522278-A1 | BENZOYPARAZINE PYRAZINES ANE THEIR USES | Foghorn Therapeutics Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023220129-A1 | BENZOYPARAZINE PYRAZINES ANE THEIR USES | FOGHORN THERAPEUTICS INC. (US) | 2023-11-16 | — | — | WO | disclosed |